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Year:
2000
| Volume: 8
| Issue: 1
| Pages: 15-19
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Actual Problem |
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PHYSICAL ASPECTS OF ENDOVASCULAR BRACHYTHERAPY
Milutin BAUCAL |
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DOI:
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Abstract: |
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Recent data suggest that intraluminal irradiation of coronary arteries in conjunction with balloon angioplasty and/or stent implantation reduces the proliferation of smooth muscle cells and neointima formation, thereby inhibiting restenosis. Irradiation of peripheral arteries in humans has yielded similar results. In this article, a review of dosimetric requirements for the irradiation of coronary arteries and peripheral blood vessels, and the physical and dosimetric characteristics of several proposed irradiation techniques will be presented. Also, current approaches to the problem of dose prescription and choice of different radioactive isotopes convenient for endovascular brachytherapy treatment will be discussed. |
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Key words:
Endovascular brachytherapy; Restenosis; Gamma emitters; Beta emitters; Radioactive stents |
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