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Year:
2000
| Volume: 8
| Issue: 1
| Pages: 7-10
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Original Article |
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IS IT POSSIBLE TO PRESUME PRIMARY CANCER SITES OF ORIGIN ON THE BASIS OF MRI PATTERN OF INTRAAXIAL POSTERIOR FOSSA METASTASIC TUMORS
Milos A. LUCIC, Katarina KOPRIVSEK, Oto ADJIC, Dusko KOZIC, Robert SEMNIC, Ivana VUKADINOVIC, Dragana DJILAS-IVANOVIC, Mladen PRVULOVIC |
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DOI:
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Abstract: |
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Background: Purpose of the study was to determine whether the native and contrast enhanced MRI pattern of detected intraaxial posterior fossa metastatic tumors may potentially suggest the origin of primary malignoma.
Methods: In 99 patients with known primary cancer, in whom non-contrast MRI brain examination on 1.5T MRI unit (Siemens Magnetom SP 63-4000) revealed tumorous lesion localized in posterior fossa using the routine protocol, paramagnetic contrast agent (Gadolinium-DTPA) was applied intravenously. After the application of the contrast agent we performed contrast-enhanced T1W scans in at least two optional planes (transversal and saggital or coronal).
Results: In great majority of the patients MRI pattern of intraaxial posterior fossa metastatic tumors was nonspecific. In 9 patients (9.09%) specific pattern was connectable with the primary malignoma site of origin. In 29 patients more (29.29%) MRI examination revealed additional data which in future patients may give a clue for further diagnostic test in revealing the primary cancer site of origine.
Conclusion: Regardless its primary site of origin, great majority of intraaxial metastatic tumors in posterior fossa demonstrate nonspecific MRI pattern, while only small number of metastasis, due to its unique features, demonstrate specific pattern which may suggest the primary malignancy site of origin. |
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Key words:
Posterior fossa, Metastasis, Magnetic resonance imaging, Gadolinium-DTPA |
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