Founded in 1993
  Year: 1999 | Volume: 7 | Issue: 2 | Pages: 53-54
  Original Article
Marko ERAK, Jovan BABIC, Dragica ERAK, Zoran KUZMANOVIC
  Background: Bladder carcinoma is a relatively rare carcinoma, about 5% of maligantn tumors in males and 3% in females. It has been most frequent in the seventh and eighth life decades. In the last decades an increased number of the diseased with this malignant illness has been noticed. The aim of this papaer is to evaluate the results of the radiotherapy of bladder carcinoma by the split-course therapy.
Methods: After the schematic treatment we applied individual treatment in that way that we determined the localization and the size of the bladder and localization of the tumor. The radiotherapy was applied according to the following protocol of the split-course radiotherapy: a total dose of 6000 cGy from the two opposite fixed fields was applied, 3000 cGy in 10 fractions, then a break of 30 days followed and then again 3000 cGy in 10 fractions.
Results: There were 148 patients with bladder carcinomas subjected to split-course radiotherapy from 1985 to 1993. If we examine the 5-year survival rate we can conclude that the 5-year survival rate was 87. 5% in the first stage, in the second stage 37 treated patients survived 5 years, in the third stage 9 lived longer than 5 years out of 21 patients treated. If we consider the total number of patients who survived 5 years we can notice that it is a high number 71 (47.9%) and that the results of our treatment are better than the results found in the world literature.
Conclusion: The contribution of the split-course radiotherapy in the treatment of bladder carcinoma resulted is in the reduction of the total time of treatment, reduced number of fractions and preservation of radiobiological efficacy.
  Key words: Bladder carcinoma: Radiotherapy; Split-course method Multiple superficial basocellular carcinomas; Basocellular naevus syndrome
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Founder and owner: Oncology Institute of Vojvodina, Serbia
Publisher: Oncology Institute of Vojvodina
Co-publisher: Faculty of Medicine, University of Novi Sad
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520