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Year:
2008
| Volume: 16
| Issue: 1-2
| Pages: 14-15
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Case Report |
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RITUXIMAB FOR PRIMARY CUTANEOUS LARGE B-CELL NON-HODGKIN’S LYMPHOMA OF THE SCALP
Colovic N, Jurišic V, Colovic M. |
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DOI:
10.2298/AOO0802014C |
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Abstract: |
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A 46-year-old man with a primary cutaneous large B-cell non-Hodgkin's lymphomas is reported. His mother died of gastric lymphoma and his sib brother is 20 years in a remission of T-cell lymphoma. He noticed the appearance of localized baldness and rash of the scalp 16 years before a hematological diagnosis was made. Diagnostic procedures performed in 2006 demonstrated progressive disease with crusted skin nodules (7x7.2cm) which exuded serous fluid. Histopathologcal and immunohistochemical results suggested the diagnosis of a primary cutaneous large B-cell non-Hodgkin's lymphoma. The patient was treated with rituximab and chemotherapy (protocol R-CHOP) and achieved a complete remission. A rather protracted indolent phase of disease, the familial history of lymphoma, and an excellent response to immunochemotherapy contributed to an unusual presentation of this patient's disease. |
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Key words:
Antibodies, Monoclonal; Lymphoma, Large Cell, Diffuse; Lymphoma, Non-Hodgkin; Scalp |
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