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Year:
1997
| Volume: 5
| Issue: 4
| Pages: 209-214
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Review Article |
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MYCOTOXINS: PART I - OCHRATOXIN A IN THE ANIMAL AND HUMAN FOOD-CHAIN
Zoran MASIC, Ranko KLJAJIC, Olivera ZUROVAC-KUZMAN, Radojka GRULOVIC |
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DOI:
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Abstract: |
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Ochratoxin A (OA) is a dihydroisocoumarin derivative, linked to L-beta phenyalanine by an amide bond. OA is produced by molds belonging to the genera Penicillium (P. verrucosum) and Aspergillus (A. alutaceus). Several forms of OA have been determined, some of which are extremely toxic for animals and humans, while others are less toxic. The presence of OA has been detected in grains of cereals, leguminosaes, pressed oilseed pellets and other forage, in animal blood, meat products, milk and dairy products, eggs, human blood and tissues and in human milk. The ability of OA to be transmitted to the animal and human food chain is attributed to its stability in plant products and long half-life for disappearance in some animal species and in humans. OA has been implicated as the causative agent of mycotoxic nephropathy in swine and other animals and it is considered a significant ethiological factor in the formation of Balkan endemic nephropathy in humans. The paper provides data on the contamination of plant products and products of animal origin with OA, as well as ochratoxicosis of animals and humans and finally, a view of the possible risk reduction for intoxication of animals and humans with OA. |
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Key words:
Ochratoxin A; Contamination; Plant products; Animal products; Ochratoxicosis; Animals; Humans |
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