Founded in 1993
  Year: 2001 | Volume: 9 | Issue: 3 | Pages: 139-143
  Original Article
  A MULTIFACTORIAL ANALYSIS OF RADON EXPOSURE AND LUNG CANCER IN THE MIDDLE URALS,RUSSIA
Vladimir LEZHNIN, Eugene POLZIK, Vladimir KAZANTSEV
  DOI:
  Abstract:
  Background: We conducted a case-control study of residential radon and lung can- cer in the town of Pervouralsk, the Middle Urals, Russia.
Methods: We administered questionnaires to collect personified data on 200 cases of lung cancer and 237 controls. A complex of 26 known risk factors of lung cancer characterized each study participant. Concentrations of radon and thoron in residences of all cases and controls were measured using solid track detectors and Markov–Terentyev aspiration method. Radiological risk was assessed using BEIR VI model. We also applied a multifactor analysis based on mathematical methods of pat- tern recognition to establish the contribution of residential radon/thoron in the devel- opment of lung cancer.
Results: Results of our multifactor epidemiologic study showed that the contribution of natural radionuclides in the development of lung cancer in the population dwelling in multistory blocks of flats in cities of the Middle Urals, Russia ranged from 0.5-1%.
Conclusion: Comparison of the two methods allowed us to conclude that this con- tribution assessed in the multifactor analysis was more precise and correct.
  Key words: Lung Neoplasms; Radon; Air Pollutants, Radioactive; Russia
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Founder, owner and publisher: Oncology Institute of Vojvodina, Serbia
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520