Founded in 1993
  Year: 2005 | Volume: 13 | Issue: 3-4 | Pages: 115-120
  Review Article
  DNA AS CLASSICAL AND QUANTUM INFORMATION SYSTEM: IMPLICATION TO GENE EXPRESSION IN NORMAL AND CANCER CELLS
Koruga D.
  DOI: 10.2298/AOO0503115K
  Abstract:
  Usually, we think about DNA as a molecular machinery system responsible to make proteins. Protein looks like a second side of DNA code because mapping function is based on a classical information system (chemical/physical) by code 43 = 64. However, in organisms like paramecium DNA works 95% as molecular machinery for proteins synthesis, while in humans it is only about 10%. Is 90% of human genetic structure "junk"? What does other 90% DNA work in human organism? What type of information system, different than classical, does DNA possess? To give answer to this question we are rethinking well-known facts of biomolecules from both classical and quantum information point of view. Basic element in our consideration is hydrogen bond, which possess both classical and quantum properties. Based on new vision of old data we develop synergetic (classical/quantum) model of DNA information processing, which may help for better understanding the functions of "junk" sequence in genetic code. We believe that "junk" sequences may be active regulatory factor of system complexity trough microtubules (centrioles) and water in living systems. Synergetic approach (classical/quantum) of information channels may open a new vision and understanding of the genomic programming and molecular interconnection on distance based on matching classical and quantum properties of hydrogen bonds and entanglement.
  Key words: DNA; Hydrogen Bonding; Genetic Code; Neoplasms; Gene Expression; Melanoma; Quantum Theory
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Founder and owner: Oncology Institute of Vojvodina, Serbia
Publisher: Oncology Institute of Vojvodina
Co-publisher: Faculty of Medicine, University of Novi Sad
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520