Founded in 1993
  Year: 2006 | Volume: 14 | Issue: 1-2 | Pages: 54-56
  Case Report
  ANAPLASTIC LARGE CELL LYMPHOMA
Tiodorovic J, Lazarevic V, Stanojevic M, Jovanovic D, Tiodorovic-Zivkovic D.
  DOI: 10.2298/AOO0602054T
  Abstract:
  Anaplastic large cell lymphoma is defined by a proliferation of large pleomorphic blasts and a constant expression of the CD30 molecule on all neoplastic cells, and has been clinically subdivided into a primary form and a secondary form. We are presenting a case of 14-year-old boy with reddish-livid papules on the skin of right half of trunk that were confluent in the lower end into solid plaque with diameter 20 x 15 cm, and enlarged lymph nodes in axilla and on neck. Lesioned skin biopsy, biopsy of lymph node and bone marrow showed pleomorphic cells, strongly CD30, and ALK positive. In our patient diagnosis was reached on the basis of morphological and immunohistochemical characteristics.
  Key words: Lymphoma, Large Cell; Cytodiagnosis; Immunohistochemistry; Child
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Founder and owner: Oncology Institute of Vojvodina, Serbia
Publisher: Oncology Institute of Vojvodina
Co-publisher: Faculty of Medicine, University of Novi Sad
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520