Founded in 1993
  Year: 2005 | Volume: 13 | Issue: 3-4 | Pages: 126-130
  Review Article
  MOLECULAR MIMICRY OF HIV GP120: POSSIBLE IMPLICATIONS ON PREVENTION AND THERAPY OF AIDS
eljkovic N.
  DOI: 10.2298/AOO0503126V
  Abstract:
  A broad range of similarities between HIV-1 gp120 and human proteins-especially those participating in immune responses-highlight gp120 as a pleiotropic protein which can influence many important functions of the human immune system. The molecular mimicry that serves to the human immunodeficiency virus as potent destructive arms against immune system could be the weak point we are in search of over decades. Examples involving sequence and informational similarities of HIV-1 gp120 and immunerelated host cell proteins important for prevention and treatment of HIV infection are presented.
  Key words: Molecular Mimicry; HIV Envelope Protein gp120; Acquired Immunodeficiency Syndrome; AIDS, Vaccines; Therapy, Investigational; Vasoactive Intestinal Peptide; Cross Reactions; Antibodies, Viral
  Read full text in PDF [Full Text]
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Founder, owner and publisher: Oncology Institute of Vojvodina, Serbia
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520