Founded in 1993
  Year: 2007 | Volume: 15 | Issue: 3-4 | Pages: 85-88
  Pilot Study
  THE FREQUENCY OF SISTER CHROMATID EXCHANGE AND MICRONUCLEI IN EVALUATION OF CYTOGENETIC ACTIVITY OF KOMBUCHA ON HUMAN PERIPHERAL BLOOD LYMPHOCYTES
Mrdanovic J, Bogdanovic G, Cvetkovic D, Velicanski A, Cetojevic-Simin D.
  DOI: 10.2298/AOO0704085M
  Abstract:
  Kombucha is a refreshing beverage obtained by the fermentation of sweetened black tea with a "tea fungus" (symbiotic culture of acetic acid bacteria and yeasts). It is consumed due to its potential beneficial effects on human health. The aim of this study was to investigate activity of Kombucha on human peripheral blood lymphocytes in vitro. We analyzed Kombucha made from different substrates: Camellia sinensis and Satureja montana, and effects of substrates alone. The frequencies of sister chromatid exchange (SCE) and micronuclei (MN) were scored as genetic endpoints and mitomycin C was used as model mutagen. Kombucha from Camellia sinensis and Camellia sinensis substrate increased frequency of MN and SCE on mitomycin C-treated and -untreated peripheral blood lymphocytes. However, Kombucha from Satureja montana reduced incidence of MN on mitomycin C-treated and -untreated peripheral blood lymphocytes, while SCE frequency was higher than control value. In our pilot study we showed for the first time that Kombucha from different substrates induced different effects on mitomycin C-treated and -untreated peripheral blood lymphocytes.
  Key words: Lymphocytes; Cells, Cultured; Beverages; Tea; Yeasts; Sister Chromatid Exchange; Micronuclei, Chromosome-Defective; Mitomycin
  Read full text in PDF [Full Text]
Next article

Previous article

Table of contents

Browse all Volumes

Search all Volumes
By keywords
By authors

  Search AoO for:
 

  Related articles in AoO:
 
About Journal | Editorial Board | Editorial Policy | Instructions for Authors | Open Access | Advertising | Payed issues | Article Submission Charge | Contact
Founder, owner and publisher: Oncology Institute of Vojvodina, Serbia
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520