Founded in 1993
  Year: 2009 | Volume: 17 | Issue: 3-4 | Pages: 56-60
Dragan R. Milicevic, Verica B. Juric, Dubravka Z. Vukovic, Miodrag M. Mandic, Tatjana M. Baltic
  DOI: 10.2298/AOO0904056M
  Background: Samples of blood, kidney, and liver per animal were randomly selected from slaughtered pigs (n=60) and analyzed for ochratoxin A.
Methods: Determination of ochratoxin A concentration in samples of kidney and liver was performed by high-performance thinlayer chromatography after immunoaffnity column clean up, while for plasma samples, a spectrofluorometric procedure was used.
Results: Of the 60 plasma samples, 60% contained ochratoxin A in the range of 2.5-33.3 ng/mL (mean 3.055.0 ng/mL), while the incidence of ochratoxin A in kidneys and liver were very similar (70% and 65%). The average ochratoxin A concentration in liver was 3.24.35 ng/g (1.2-19.5 ng/g) and in kidneys was 3.974.47 ng/g (1.3-22.0 ng/g). A statistically significant difference (p<0.01) was found between region Baeka Topola and Kovilj for both liver and kidney samples. In kidney samples originating from region Kovilj and Senta, a statistically significant difference (p<0.01) was found. Mean distribution followed the pattern: kidney>liver>serum (100>80.8>77%). The results from this survey indicated that there was a strong correlation between the ochratoxin A level in serum and liver as well as in the ochratoxin A serum in kidney (r=0.884 and r=0.896, respectively) while the strongest correlation was found between the ochratoxin A level in liver and in kidney (r=0.970).
Conclusion: The results of present study show that pork tissues as well as pork products are considered an important source of ochratoxin A in humans.
  Key words: Ochratoxins; Aspergillus ochraceus; Tissues; Swine; Mytotoxins
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Founder, owner and publisher: Oncology Institute of Vojvodina, Serbia
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520