Founded in 1993
  Year: 2010 | Volume: 18 | Issue: 1-2 | Pages: 32-35
  Case Report
  ANTIESTROGEN THERAPY IN RECURENT OVARIAN CANCER RESULTING IN 28 MONTHS OF STABLE DISEASE: A CASE REPORT AND REVIEW OF THE LITERATURE
Rajul Kothari, Peter Argenta, Jeffrey Fowler, Jori Carter, William Shimp
  DOI: 10.2298/AOO1002032K
  Abstract:
  Hormonal therapy for adjuvant treatment of ovarian cancer may provide a low toxicity option in some patients with refractory disease. A 53 year-old patient with stage IIIC papillary serous ovarian cancer previously treated with multiple chemotherapy regimens with platinum-resistant disease was treated with antiestrogen therapy for 28 months before requiring reinstitution of cytotoxic chemotherapy. Hormonal therapy may be effective in a subset of epithelial ovarian cancer patients with endocrine sensitivity and should be considered in the treatment of platinum-resistant patients.
  Key words: Ovarian Neoplasms; Antineoplastic Agents, Hormonal; Selective Estrogen Receptor Modulators; Tamoxifen; Aromatase
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Founder, owner and publisher: Oncology Institute of Vojvodina, Serbia
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520