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Year:
1997
| Volume: 5
| Issue: 3
| Pages: 121-128
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Review Article |
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AUTOMATIC CONTROL THEORY APPLIED TO NORMAL AND CANCER CELL PROLIFERATION KINETICS
Jelena BATINIC, Lidija MATIJA, Dragutin DEBELJKOVIC, Milena POKRAJAC, Djuro KORUGA |
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DOI:
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Abstract: |
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In this paper, a short review of the existing mathematical models of cell proliferation kinetics is given. The multicompartmental model of the healthy and malignant cells with control in state space is given. The optimization method of the therapeutic process, which would an optimal drug administration make possible in the manner that maximizes the recovery of the normale tissue and the destruction of the tumor tissue is presented. The basic concepts of the fuzzy logic theory in the biological systems modeling with an example of the fuzzy system for optimization of therapeutic process are proposed. |
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Key words:
Cancer cell; Modeling; Fuzzy logic; Automatic control; Artificial neural networks |
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