Founded in 1993
  Year: 1998 | Volume: 6 | Issue: 2 | Pages: 57-58
  Original Article
  THE ROLE OF ERS (ENDORECTAL SONOGRAPHY) IN THE CLINICAL STAGING OF RECTUM ADENOCARCINOMA
Eva PAPADOPOULOU, Pascale ROMESTAING, Francoise MORNEX, Jean Pierre GERARD
  DOI:
  Abstract:
  Background: To evaluate the significance of perirectal lymph nodes, detected by endorectal sonography (ERS) in patients treated of rectal adenocarcinoma.
Methods: From 1980 to 1993, 125 patients (10 N1) were treated by radiation therapy alone (contact therapy, EBRT Iridium 192 implants) in radiation department of H(tm)pital Lyon Sud in Lyon and 158 patients (36 N1) were treated by preoperative EBRT.
Results: For patients treated with contact therapy alone, only 3 perirectal lymph node relapses were observed. No loco regional relapse for patients treated by contact and EBRT. Out of 158 patients treated by preoperative irradiation, 5-year survival was 90% for uNO vs. 50% for uN1 : p = 0.04.
Conclusion: ERS is valuable for staging of rectal adenocarcinoma. For uN1 patients, contact x-ray alone is not recommended. For inoperable patients a combination of EBRT and a local boost with contact x-ray therapy and/or Iridium 192 is beneficial and can control uN1 patients.Preoperative radiation therapy is another alternative to control uN1 patients with results comparable to postoperative radiation with chemotherapy.
  Key words: Rectal, adenocarcinoma; Radiation therapy; Endocavitary irradiation; Transrectal ultrasound; Clinical staging
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Founder, owner and publisher: Oncology Institute of Vojvodina, Serbia
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520