Founded in 1993
  Year: 2001 | Volume: 9 | Issue: 1 | Pages: 21-25
  Actual Problem
Mirna DJURIC, Tamara ZIKIC
  Peripheral lung cancer makes a large proportion of solitary peripheral pulmonary lesions (SPPL), so their early discovery and diagnosis are crucial, especially because of their asymptomatic development. The paper reviews clinical and radiological features of malignant SPPLs, and the applications of potential diagnostic procedures. Our study included a hundred of patients with a SPPL observed after X-ray examination of chest. All the examined patients underwent a complete diagnostic procedure including bronchoscopy and transthoracic aspiration biopsy. Of the total of 100 SPPLs included in this examination, 70% were malignant of which the most frequent was adenocarcinoma (67.1%), followed by squamous cell carcinoma (24.3%), small-cell lung cancer (4.3%) and metastatic lesions (4.3%). Malignant SPPLs usually affected persons between 50 to 59 years of age, more frequently males; most of them were smokers, and developed no symptoms. SPPLs were commonly localized in the right lung, and appeared in the size of 3 to 3.9 cm. Bronchoscopy revealed the etiology of SPPLs in a small number of cases, unlike transthoracic aspiration biopsy, which disclosed the etiology of 64% of these lesions. Transthoracic aspiration biopsy is doubtlessly a method of choice in preoperative diagnostics of SPPL, and achieves a high level of specificity, sensitivity and accuracy. Thoracotomy is also a method of choice when other diagnostic procedures fail to provide a definite diagnosis of SPPL.
  Key words: Coin Lesion, Pulmonary; Lung Neoplasms+diagnosis; Biopsy, Needle
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Founder, owner and publisher: Oncology Institute of Vojvodina, Serbia
Online since 1997 (Abstracts only); 2000 (Abstracts and Full text)
ISSN: 0354-7310 eISSN: 1450-9520