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Year:
2001
| Volume: 9
| Issue: 1
| Pages: 39-42
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Case Report |
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HUMAN HERPESVIRUS 8 DNA SEQUENCES IN CLASSIC KAPOSI’S SARCOMA
Mirjana POLJACKI, Verica DJURAN, Milan MATIC, Fabriana VACCINA, Maria Grazia TAMASSIA, William GENNARI, Vladimir BRAKUS, Zorica GAJINOV |
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DOI:
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Abstract: |
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Recent evidence about human herpesvirus 8 DNA sequences in Kaposi's sarcoma patients with or without HIV infection indicates the possible impact of this virus in etiopathogenesis of this disease. To confirm this hypothesis, two samples of cutaneous lesions and one extracutaneous sample from patient with classic Kaposi's sarcoma have been analyzed for the presence of human herpesvirus 8 DNA sequences. Identification of viral DNA sequences was performed with nested PCR method. In all three samples presence of identical DNA sequences of human herpesvirus 8 have been documented. In consistence with previous research obtained results support the hypothesis of possible role of human herpesvirus 8 in pathogenesis of classic Kaposi's sarcoma. |
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Key words:
Sarcoma, Kaposi; Skin Neoplasms; Herpesvirus, Kaposi Sarcoma-Associated |
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