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COMPLICATIONS
DURING THE CONVENTIONAL RADIOTHERAPY OF COLORECTAL CARCINOMA
Bokorov
B, Vujošević B, Ilić A, Breberina M.
Institute
of Oncology Sremska Kamenica, Sremska Kamenica, Serbia
and Montenegro
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ABSTRACT
Since the middle
of 2000, we have been applying the modified Swedish protocol of
therapy for locally advanced colorectal carcinoma in our Institute.
After 5 weeks of radiotherapy (50Gy/25f from two lateral and one
dorsal field, or usually from two opposite fields) the next step
is mesorectectomy, which is done between fourth and sixth week
after the end of the treatment. We preoperatively irradiated 37
(28%) out of 134 analyzed patients. To some of our patients we
applied concomitant chemotherapy using FA/LKV on day 1, 10, 11,
20 and 21of radiotherapy, half an hour before irradiation. Diarrhea,
proctitits with anal hemorrhage, pain, colpitis, abacterial cystitis
and hemorrhagic cystitis appeared as early complications. The
late complications, such as hernia, ileus, and adhesions, were
the consequence of the operation itself, although we also registered
a very strong postirradiated fibrosis, which led to ileus and
death (small bowels). The appearance of rectovaginal fistula is
observed within one year after the end of the treatment. As the
late complications appeared dryness of vagina and impotency which
is, according the literature, a consequence of the operation.
In our team, gastroenterologists, oncologists, gynecology oncologists
and urologists take care of the complications. Pain control is
under the jurisdiction of anesthesiologists.
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